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★★★★★
4.9
4,200+ reviews
Clinic-grade salmon DNA in one daily step. It helps skin make more of its own collagen, so it looks smoother, plumper and brighter with every use.
1-Month Dose
SAVE $58
20ml · 2 × 10ml ampoules
261 AED/mo · billed monthly
261 AED/mo
$2.30/day
436 AED
3-Month Dose
SAVE 50%
60ml · 6 × 10ml ampoules
654 AED · billed every 3 months
218 AED/mo
$1.93/day
436 AED
One-time purchase for 436 AED
Free shipping · 30-day money-back · Ships today
Details
Targets Fine lines, firmness, wrinkles, skin barrier, dark spots, dullness and dryness.
Suited for All skin types, including sensitive.
Formulation Highly concentrated, fragrance-free ampoule.
Amount 20ml (2 × 10ml) for one month, or 60ml (6 × 10ml) for three. Each 10ml ampoule lasts two weeks with daily use.
How to use
Use daily after cleansing, and after toner if you use one. Apply to face and neck, then follow with your usual skincare.
Shipping
Orders process in 1–2 business days. USA delivery takes 2–6 business days and GCC takes 1–3. Everything ships locally, so there are no duties or taxes.
Ingredients
Aqua, Glycereth-26, Glycerin, Dimethicone, Polyglyceryl-3 Stearate, Cetearyl Olivate, Caprylic/Capric Triglyceride, Niacinamide, Methylpropanediol, Polysorbate 60, Butylene Glycol, Stearic Acid, Cetyl Alcohol, Carbomer, Arginine, Chlorphenesin, 1,2-Hexanediol, Allantoin, Stearyl Alcohol, Ethylhexylglycerin, Sodium DNA, Disodium EDTA, Adenosine, Pentylene Glycol, Myristyl Alcohol, Sodium Hyaluronate, Madecassoside, Lauryl Alcohol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid.
PDRN Ampoule
Money Back Guaranteed · Free Shipping
4.9 from 4,200+ reviews
What people noticed first.
As seen in
ALLURE
VOGUE
COSMOPOLITAN
The results
Clinical results, at home.
An independent 12-week study, graded by dermatologists, with no injectables.
Individual results vary. For cosmetic use only. Not intended to diagnose, treat, cure or prevent any disease.
92%
reported smoother, brighter-looking skin after one use
86%
said skin looked smoother, plumper and more radiant with consistent use
35%
increase in collagen production during clinical testing
Why This Is Different
Everything else is a bandaid.
Most anti-aging does one of four things to your skin. None of them get it repairing itself again.
Don’t force your skin. Remind it.
Wake
Yurslf Pdrn
What It Does
Sends skin the signal to start its own repair work again.
The Catch
✓ Skin keeps doing the work itself, so results build week after week.
Trusted by Beauty Insiders
They don't just
recommend it. They use it.
Why it works
Where creams stop, this keeps going.
Salmon DNA is close enough to our own that skin recognizes it and responds the way it knows how, by repairing itself.
1
It rebuilds, not coats
PDRN signals fibroblasts to produce collagen and elastin. It rebuilds structure instead of just coating the surface.
2
Clinic strength, at home
50,000 PPM is the highest topical PDRN available, and the same active used in in-clinic salmon-DNA facials.
3
A glow that compounds
It isn't a one-night glow. With daily use, results build the longer you stay with it.
What's inside
Four actives. Nothing for show.
A highly concentrated formula. Every ingredient earns its place: nothing for marketing, nothing for filler.
SALMON DNA · 50,000 PPM
Skin rejuvenator
Stimulates collagen, promotes cell regeneration and softens fine lines, for firmer, brighter skin.
HYALURONIC ACID COMPLEX
Hydration
Several molecular weights hydrate at different depths and lock moisture in.
NIACINAMIDE
Brightener and barrier
Improves clarity and texture, and supports a stronger, more even-looking barrier.
MADECASSOSIDE
Soother
A purified active from Centella asiatica that soothes and supports the skin's own protective barrier.
FULL INGREDIENT LIST
Aqua, Glycereth-26, Glycerin, Dimethicone, Polyglyceryl-3 Stearate, Cetearyl Olivate, Caprylic/Capric Triglyceride, Niacinamide, Methylpropanediol, Polysorbate 60, Butylene Glycol, Stearic Acid, Cetyl Alcohol, Carbomer, Arginine, Chlorphenesin, 1,2-Hexanediol, Allantoin, Stearyl Alcohol, Ethylhexylglycerin, Sodium DNA, Disodium EDTA, Adenosine, Pentylene Glycol, Myristyl Alcohol, Sodium Hyaluronate, Madecassoside, Lauryl Alcohol, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid.
The ritual
Morning or night, in under a minute.
STEP 01
Uncap
Start on clean, towel-dried skin.
STEP 02
Unlock
Unlock the pen and release 1–2 drops per area.
STEP 03
Apply
Press gently into face and neck.
STEP 04
Layer
Let it sink in, then moisturizer, SPF or makeup.
What to expect
Week by week.
WEEKS 1–2
Glow and hydration
These are the first things most people notice.
WEEKS 4
Texture
Skin renews in roughly four-week cycles. Around now it starts to feel denser and smoother.
WEEK 8-12+
Firmness and fine lines
This is the compounding part, and why the 3-month dose is the one most people choose.
The difference
Better skin. Less spend.
YURSLF
THE OLD WAY
✓
Rebuilds skin at the cellular level
✕
Only hydrates the surface
✓
Real salmon PDRN at 50,000 PPM
✕
Plant substitutes at 5,000–10,000 PPM
✓
One gentle daily step, sensitive-safe
✕
A stack of serums and clinic visits
218 AED/mo
2000 AED+/mo
One daily ampoule in place of the serums, essences and in-clinic aesthetics.
Watch · 2 min
1 in 3 Women Treat Their Skin Wrong
Watch Felicia, Medical Esthetician explain the dos and dont's of skincare.
Questions
Everything you
might be wondering.
Why should I subscribe?
You can cancel at any time, there are no commitments. Subscribing is the best way to get the full benefits while saving significantly.
This product is designed for daily, consistent use, not occasional application. With regular use, the results build over time: supporting collagen production, strengthening the skin barrier, and helping skin look brighter, healthier, and more resilient.
Think of it like a daily supplement for your skin. One time use can’t deliver lasting results.
Is Salmon DNA Pregnancy Safe?
Salmon DNA is a topical ingredient that does not enter the bloodstream and is considered suitable for use during pregnancy.
Does it hurt or sting like retinol?
Not at all. Unlike retinol or other strong actives, the ampoule is completely pain-free — no stinging, peeling, or purging. It actually supports your barrier, which is why it's safe for sensitive skin.
Can I use this with tretinoin or retinol?
Yes, absolutely! Salmon DNA can be used alongside tretinoin or retinol and is often layered to help support skin repair and barrier recovery. We always recommend patch testing prior to full use, especially when combining with active ingredients, to ensure your skin responds well.
How does Salmon DNA work in the skin?
It binds to A2A purinergic receptors, activating a repair process at the cellular level. This stimulates fibroblasts to produce more collagen and elastin, increases skin turnover, and reduces inflammatory responses.
Will it smell like fish?
Not at all. Salmon DNA and other cosmetic-grade PDRNs are purified and odorless. The final product has no scent or fish-related properties.
What exactly is PDRN?
PDRN (polydeoxyribonucleotide) is a regenerative ingredient used in clinics to stimulate skin repair. It signals your own cells to renew — building collagen, accelerating turnover, and improving hydration. It's the most clinically studied ingredient in regenerative skincare.
Is it really made with salmon DNA?
Yes. We use real salmon-derived PDRN rather than synthetics or plant substitutes, because salmon DNA is the most bio-compatible with human skin, which is what makes it work so well.
Can I use it with my other actives and makeup?
Yes. It has a silky, non-sticky finish that layers beautifully under makeup and pairs with every other step in your routine — serums, moisturizer, SPF. No conflicts, no pilling.
How soon will I see results?
Many members notice glow and hydration within the first couple of weeks. Firmness and fine-line improvements build over 8+ weeks — this is renewal that compounds, so consistency matters. That's why the 3-month plan is most popular.
What’s the difference between this and injectable PDRN like Rejuran?
Rejuran is an injectable treatment used in clinics, while Salmon DNA is a topical-grade version that can be used daily at home. Both use salmon DNA, but Salmon DNA is processed into low molecular weight fragments for better absorption through the skin barrier.
Are there any clinical studies to back this up?
Yes. Salmon DNA has been clinically studied since the early 2000s in Italy and Korea. A 2016 study (Int. J. Mol. Sci.) confirmed its anti-inflammatory and regenerative properties, and a 2013 study (Dermatology Research and Practice) validated its safety for dermal use.
How do I use Salmon DNA with my existing skincare routine?
Apply it to clean skin before heavier serums or moisturizers. It layers easily with most routines.
30-day promise
Glowing skin, or
your money back.
Give the ritual a full 30 days. If your skin doesn't look firmer, brighter and more hydrated, we'll refund you, and you don't have to ship anything back.
Free shipping · Pause or cancel anytime